17 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... other elements Nephritic ... • Breaks in GBM ... #nephrology #nephritic ... #nephrotic #comparison
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
- Nephritic and ... Nephrotic Syndromes ... to GBM disruption ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology ... #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... nephropathy • Thin GBM ... • Hereditary nephritis ... ) • Anti-GBM ... and >3.5g/day (nephrotic
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... RPGN • Anti-GBM ... #diseases #nephrology ... comparison #table #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
nephropathy, lupus nephritis ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... #Differential #Diagnosis ... #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... clusters because nephritic ... Nephrocalcinosis causes ... #nephrotic #syndrome ... #nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
Causes of acute ... vascular supply; glomerular ... GBM, Glomerular ... #Diagnosis #AKI ... #Sites #Nephrology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus Nephritis ... Henoch-SchonIein Purpura Anti-GBM ... to Kidney: Anti-GBM ... involvement: Anti-GBM
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... infections are common causes ... testing #workup #diagnosis ... glomerulonephritis #nephrotic ... #nephritic #nephrology