11 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... hematuria. ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... disease • ... IgA, post-strep, lupus ... • Pauci-immune disease ... nephrotic range) proteinuria
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... (hematuria, proteinuria ... IgA nephropathy, lupus ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... granulomatosis: • EBV-associated ... lymphoproliferative disease ... differential #diagnosis #causes ... #radiology #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... Complex: Systemic lupus ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... (non-nephrotic proteinuria ... , hematuria) • ... nephrotic-range proteinuria ... and CNS • Headache
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... impairment), heart disease ... Nephrocalcinosis causes ... Hematuria may be ... nephrotic #syndrome #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... , hematuria) • ... Inflammatory eye disease ... Goodpasture's cause ... grade proteinuria
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... Demyelinating disease ... caused by the JC ... effect/Edema • EBV ... InfectiousDiseases #Neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
multiplex • Hematuria ... , proteinuria, rapidly ... tract, and often causes ... such as systemic lupus ... #rheumatology #classification