19 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... pressure - Raised Proteinuria ... - ++ Hematuria ... edgarvlermamd - Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... syndrome: • ... Brown urine - Proteinuria ... • Nutcracker syndrome ... #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... proliferative • Anti-GBM ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... PCR 50% sensitive ... granulomatosis: • EBV-associated ... differential #diagnosis #causes ... #radiology #neurology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... Nephrocalcinosis causes ... Hematuria may be ... #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Dyspnea, Fever, Hematuria ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
• Renal: (AKI, proteinuria ... , hematuria) • ... recent DAN) • EMG/NCS ... Goodpasture's cause ... grade proteinuria
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... Hyperoxalirua, Heavy Proteinuria ... - UTI caused by ... Pink Urine: • Hematuria ... Differential #Diagnosis #nephrology