33 results
Kidney Biopsy - Diagnosis Algorithms
1) Normal Glomerulus by LM
2) Glomerular Crescents
3) Double Contours of GBM
4) Endocapillary
2) Glomerular Crescents ... Double Contours of GBM ... Diagnosis #Algorithm #nephrology ... #pathology
Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678035/

Mycophenolate versus Azathioprine as Maintenance Therapy
www.ncbi.nlm.nih.gov/pmc ... VisualAbstract #Nephrology ... #EBM #MMF
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
a patient with crescentic ... SEM #clinical #pathology ... #hematology #nephrology
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This image shows acellular scanning EM with a fibrocellular crescent with entrapped RBCs. The glomerulus is
acellular scanning EM ... fibrocellular crescent ... fibrocellular #crescent ... SEM #clinical #nephrology ... #pathology
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Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
• Breaks in GBM ... • Crescent formation ... spectrum #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
proteinuria) - Crescent ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Differential #Diagnosis #Nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
toxo IgG • CNS PCR ... granulomatosis: • EBV-associated ... disease • 30% present ... causes #radiology #neurology
This image shows acellular scanning EM with empty lacunar spaces of a fibrocellular crescent previously occupied
acellular scanning EM ... fibrocellular crescent ... fibrocellular #crescent ... SEM #clinical #nephrology ... #pathology
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Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Dextrose in water @ 3cc ... MH/CCF/CWRU EM ... rate #management #nephrology
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
minor criteria present ... aggregates) in BM ... are atypical on BM ... unless an AHN is present ... mastocytosis #hemepath #pathology