15 results
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology ... Effects of Insulin Deficiency ... #Insulin #Deficiency ... #DKA #Ketoacidosis ... #Endocrinology
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin deficiency ... insensitivity #DKA ... #Pathophysiology ... #Endocrinology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... relative insulin deficiency ... details of the pathophysiology ... #Pathophysiology ... #Diabetes #Endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs/symptoms ... of HHS/DKA: Both ... , hypotension) DKA ... : Short course (
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... : - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
21-Hydroxylase Deficiency ... - Signs and Symptoms ... density, Adult short ... #Signs #Symptoms ... #diagnosis #endocrinology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... amount of enzyme deficiency ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
with vitamin A deficiency ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... diagnosis #signs #symptoms