5 results
REVISE - Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical
Randomized Clinical Trial ... feasibility of a larger trial ... #Prophylaxis #CriticalCare ... #Withholding #VisualAbstract ... #EBM
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
cardiovascular causes ... Spironolactone #HFpEF ... dCHF #Cardiology #EBM ... #VisualAbstract ... #Trial
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... Randomized Clinical Trial ... #TTM48 #TTH48 #CriticalCare ... #ICU #VisualAbstract ... #EBM
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Libman Sacks) • Atrial ... myxoma • Hypercoagulable ... Septic Emboli Cause ... Treat underlying cause ... #diagnosis #management
SMART Trial - Balanced Crystalloids versus Saline in Critically Ill Adults 

N Engl J Med 2018;
SMART Trial - Balanced ... death from any cause ... Wilkinsonjonny #SMART #Trial ... Crystalloids #Saline #VisualAbstract ... #EBM #CriticalCare