12 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... - Tumor lysis syndrome ... infusions) - Metabolic ... potassium #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Heat stroke - Metabolic ... or compartment syndrome ... Treatment of underlying ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... - Tumor lysis syndrome ... infusions) - Metabolic ... potassium #high #nephrology
Side Effects of Atypical and Typical Antipsychotics - Comparison Table
Atypical antipsychotics: Risperidone, Quetiapine, Olanzapine, Amisulpride, Ziprasidone
are common to all ... , weight gain, metabolic ... syndrome, increased ... Antipsychotics #SideEffects ... Table #Psychiatry #Pharmacology
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
considered 2nd line treatment ... Antagonism - Block ACh ... body • Cardio-metabolic ... SecondGeneration #Mechanisms #SideEffects ... #pharmacology #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Blood transfusion, Hypercalcemia ... circulation: MCA ACA ... Drug toxicity, Metabolic ... epilepticus Treatment ... underlying cause • Treatment
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... Mg, preferably Cl ... In persistent hypokalemia ... #nephrology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
inevitably leads to Metabolic ... Metabolic Acidosis ... the ECF causes Hyperkalemia ... management #diagnosis #treatment ... #pharmacology #