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diagnosis management causes differential lysis oncology rhabdomyolysis tumor classification emergencies hematology hemeonc nephrology oncologic potassium summary uricacid
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... - ACS, AKI, acute ... Spontaneous if high ... hydration - Hyperkalemia ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
, Compartment syndrome ... , Electrical injury ... HIV, Influenza, TSS ... Shift of extracellular ... Dialysis for severe hyperkalemia
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... ) occur in high ... grade lymphoma & Acute ... #TLS #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... HIV, Influenza, TSS ... or compartment syndrome ... Shift of extracellular ... Treatment:
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... low Ca - q8 h TLS ... anticoagulation Leukostasis ... plasmapheresis Hypercalcemia ... → no immediate treatment
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
extracellular shift ... neuromuscular injury ... injury F. ... antiphospholipid syndrome ... Differential #Diagnosis #High
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