22 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... Treatment of TLS ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... with Ca only if EKG ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... - 6.4 mmol/L - Treatment ... clinical scenario, ECG ... Gluconate IV Shift ... recurrence #Hyperkalemia
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts ... plasma insulin (treatment ... diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... excess and related syndromes
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... DrEricStrong #BRASH #Syndrome
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... injury, etc) ECG ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia ... management #algorithm #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... or compartment syndrome ... Shift of extracellular ... Treatment of underlying
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Shift of extracellular ... oxidative iniury Treatment ... Dialysis for severe hyperkalemia
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Congenital long QT Syndrome ... Hypomagnesemia • Hypokalemia ... • Hypocalcemia ... (rarely) Treatment ... load: 25-50 mg/kg