26 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
of the cell -> Bilateral ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Compression/injury of Lateral ... are typically unilateral ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
and Headache - Differential ... photophobia - Bilateral ... headache: - Bilateral ... meningeal irritation signs ... #diagnosis #ophthalmology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
radiation -> Bilateral ... > Keratoconus Signs ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Intermittent Bilateral Exophthalmos (Alternating Exophthalmos and Enophthalmos) on Physical Exam

Observing this patient in silence for a
Intermittent Bilateral ... this patient- bilateral ... Differentials for ... #Alternating #Bilateral ... clinical #video #ophthalmology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... tissue expansion (e.g ... endocrinology #pathophysiology
Floaters - Differential Diagnosis Framework

What?
Vitreous Floaters:
• Microscopic collagen fibers within the vitreous that tend to clump
Floaters - Differential ... Patients As: • Black spots ... the vision • Spots ... hypotension - bilateral ... Diagnosis #Ocular #ophthalmology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
years with: • Unilateral ... • Lhermitte’s sign ... Signs and symptoms ... VEP’s: EEG of visual ... taper 3-7 days - Short
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... conditions listed in differential