11 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... fractures • Short ... #genetics #pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... severe clinical complications ... hyperparathyroidism Treatment ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
(IRIS) - Pathophysiology ... OI (in CM) - Short ... duration or OI treatment ... #Inflammatory #Syndrome ... #AIDS
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... Signs of poor perfusion ... Signs of congestion ... acute coronary syndrome ... #diagnosis #differential
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... Nasal polyps and signs ... advanced disease Complications ... mycobacteria Treatment ... Bronchiectasis #pulmonary #differential
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... implications. ... mobilizes fatty acids ... for Refeeding Syndrome ... #diagnosis #differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Hypocalciuria (spot ... ratio 0.5%) Differential ... diarrhea Potential Complications ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... nodes • Roth’s spots ... Cholesterol emboli syndrome ... hematuria, + RF Treatment ... destructive lesion • Complications