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diagnosis management symptoms syndrome activation antimda5dm autoantibodies autoimmune behcet classification dermatology dermatomyositis disease erythematosus gca giantcell lupus macrophage mas mimickers
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
-74%] • Blood tests ... anti-NXP2 Abs Lung ... • Arthralgia/arthritis ... #AntiMDA5 #Dermatomyositis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
is a skin prick test ... Behcet disease) Differential ... , AS Treatment: ... diagnosis #management #signs ... #symptoms #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... the “Chewing gum test ... Treatment of GCA ... them, but urgent rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... Liver function tests ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ear disease Differential ... purpura: strong sign ... retinopathy Lab Tests ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Diagnostic Tests ... ) • Shawl sign ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
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