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diagnosis management hematology reactions classification cryofibrinogenemia cryoglobulins erythematosus hemophagocytic hlh lymphohistiocytosis systemic transfusion transfusions treatment types vasculitis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Manifestations: Malar ... versus DIL • ... Positive in 60-80% of cases ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Summary Cryoglobulins ... causing endothelial injury ... • They can cause ... (e.g. systemic lupus ... classification #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Summary ... of fibrin split products ... which can plug blood ... • Fibrin split products ... cryoglobulins • Negative causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... One Pager Summary ... Related Acute Lung Injury ... Blood products contain ... tested include: Malaria
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Leishmaniosis, malaria ... Autoimmune diseases: SLE ... management #treatment #summary ... #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... Causes purpura & ... Related Acute Lung Injury ... Blood products contain ... tested include: Malaria
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