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hematology hemophagocytic hlh lymphohistiocytosis crisis erythematosus hemeonc nephrology renal scleroderma sle src summary syndrome systemic treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... #Macrophage #Activation ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... of macrophages ... Leishmaniosis, malaria ... #management #treatment ... #summary #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... (often termed MAS-HLH ... : Macrophage Activation ... - Cytopenias (anemia ... #Management #Hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... is unknown but may ... endothelial cell activation ... Renal #Crisis #rheumatology ... #management
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