8 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... with leukopenia, anemia ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Photosensitivity • Malar ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... #Rheumatology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
microangiopathic hemolytic anemia ... is unknown but may ... endothelial cell activation ... #Crisis #rheumatology ... #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
myopathy • Anti MAG ... (-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... #Differential #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May recur; 25% of ... , DIC, hypoTN, renal ... tested include: Malaria ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
May recur; 25% of ... , DIC, hypoTN, renal ... tested include: Malaria ... #Transfusions #diagnosis ... #management #hematology
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
thrombocytopenia, and renal ... No hemolytic anemia ... Babesiosis • Plasmodium ... diagnosed in the ... tests of liver and renal
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... by uncontrolled activation ... (often termed MAS-HLH ... - Cytopenias (anemia ... #Management #Hematology