12 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... B19 infection Malar ... • Rheumatic fever ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
should be interpreted ... erythematosus (SLE ... erythematosus (SLE ... : Lupus (SLE), Systemic ... #patterns #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
of Lumbar Spine and ... secondary) • Rheumatoid ... with Systemic Lupus ... Erythematosus (SLE ... ), should have other
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
bacterial), acute rheumatic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... remember yellow and ... #rheumatology #
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... in at least 2 joints ... low C4, Low C3 and ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... RF test should ... diagnosis #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... vasculitis, rheumatoid ... Arthritis: • Joint ... Photosensitivity • Malar
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... Diagnosis: Systemic rheumatic ... LFT • ESR • ANA ... SLE) • Urinalysis ... #classification