11 results
diagnosis management hematology sle druginduced erythematosus hemophagocytic lymphohistiocytosis summary syndrome systemic acidosis activation arthritis behcet causes comparison differential dil elevation
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar ... versus DIL • Laboratory ... Workup: - ANA ... life-threatening • Treatment ... Evolution: Chronic disease
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Leishmaniosis, malaria ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... calcium-b) • Laboratory ... Workup: - ANA ... Evolution: Chronic disease ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... • Bicytopenia Treatment ... • Infection should ... antibiotic therapy should ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fever) and laboratory ... Classification: ... Non-autoimmune rheumatologic ... with: • Minimal laboratory ... Photosensitivity • Malar
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... RF test should ... more time for the laboratory ... back pain) • HLA-B27
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... common in Asia • HLA-B51 ... pathognomonic laboratory ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... number of sites of disease ... Hodgkin Lymphoma Treatment ... lymphoma #diagnosis #classification ... #hematology #oncology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
& NPSLE rare, Malar ... calcium-b) • Laboratory ... Workup: - ANA ... #DIL #rheumatology ... #diagnosis #treatment
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