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diagnosis hematology management arthritis differential disease erythematosus laboratory leukemia macrophage oncology pediatrics peds pmr polymyalgia purpura rheumatic rheumatica rheumatoid syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... manifestations: from easy bruising ... erythematosus [SLE ... with leukopenia, anemia ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... (systemic lupus ... - Bernard—Soulier ... #Causes #peds #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... ANAs RF test should ... the presence of anemia ... diagnosis #testing #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... -> AML: Blast crises ... PLT: Petechiae, bruising ... - infiltrates (anemia ... #Leukemia #Hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... motion in the shoulders ... describe difficulty rising ... • Normocytic anemia ... Diagnosis #Management #Rheumatology
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