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diagnosis hematology differential classification common cvid extravascular hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular oncology pediatrics peds purpura thrombocytopenia variable
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... • Infections: Malaria ... #anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy arising ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... #oncology #management
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... SLE (systemic lupus ... - Bernard—Soulier ... #Causes #peds #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hepatitis • Lymphoma ... • Nodules • Lymphoid ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes
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