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diagnosis differential management sle erythematosus hematology systemic ana anemia antibodies arthritis bleeding bruising causes comparison disease extravascular hemolysis hemolytic hemostasis
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Anti-phospholipid) M Malar ... Discoid Rash A Antinuclear ... sle #systemic #lupus ... erythematosus #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... & NPSLE rare, Malar ... Manifestations: Malar ... Lupusreference #druginduced ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar ... , oral ulcers, Lupus ... of SLE versus DIL ... Management #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... healthy adults, and should ... , Drug-induced Lupus ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... & NPSLE rare, Malar ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation (DIC ... usually IgG) (e.g. lupus ... • Infections: Malaria ... differential #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... of factor VII should ... disease • Acute DIC ... Differential #Diagnosis #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... ANAs RF test should ... diagnosis #testing #Rheumatology
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