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sle differential erythematosus systemic management ana antibodies arthritis autoantibodies causes comparison dil disease extravascular hemolysis hemolytic imdamnsharp intravascular laboratory mimickers
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Anti-phospholipid) M Malar ... Discoid Rash A Antinuclear ... Pleuritis) H Hematologic ... erythematosus #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #hematology #anemia
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... Arthritis 69% - Malar ... - Hemolytic anemia ... Differential Diagnosis ... #differential #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... healthy adults, and should ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Manifestations: Malar ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Photosensitivity • Malar ... lymphopenia, low PLT • Anemia ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... ANAs RF test should ... the presence of anemia ... #testing #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... & NPSLE rare, Malar ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
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