13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... BrighamChiefs #Bone #Joint ... differential #diagnosis #causes ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... differential #diagnosis #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Discontinuation of causal ... Manifestations: Malar ... #sle #comparison ... #table #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... life-threatening causes ... #Presentation #comparison
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... (in a shawl sign ... interphalangeal joints ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... noninflammatory Signs ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
interphalangeal joint ... with joint-space ... mass and NO prior signs ... • This case should ... diagnosis #msk #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and pain of the joints ... Causes: - Idiopathic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... of factor VII should ... discern these causes ... Differential #Diagnosis #Hematology