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diagnosis differential arthritis erythematosus systemic druginduced joint management msk workup antibodies autoantibodies classification comparison dil disease imdamnsharp laboratory mimickers mnemonic
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-phospholipid) M Malar ... Discoid Rash A Antinuclear ... Antibody (ANA) ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... context of other symptoms ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... & NPSLE rare, Malar ... Manifestations: Malar ... Workup: - ANA ... #table #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Photosensitivity • Malar ... : • Symptoms limited
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... constitutional symptoms ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... ) - Antinuclear ... low back pain) ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... & NPSLE rare, Malar ... is rare in DIL, SCLE-DIL ... constitutional symptoms ... #DIL #rheumatology
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