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Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
combined with a low platelet ... The exact cause ... antibodies which cause ... platelet activation ... thrombocytopenia #COVID #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... Coagulation #diagnosis #causes
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Differential #Diagnosis #causes ... #Platelets #hematology
Formation of a Hemostatic Platelet Plug #Hemostatic #Platelet #Plug #Formation #Pathophysiology #Hematology
of a Hemostatic Platelet ... #Hemostatic #Platelet ... Plug #Formation #Pathophysiology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
Causes of Acquired Platelet Dysfunction #Acquired #Platelet #Dysfunction #Causes #differential #Diagnosis #hematology
Causes of Acquired ... Platelet Dysfunction ... #Acquired #Platelet ... #Dysfunction #Causes
Inhibitors of Platelet Aggregation #Antiplatelet #Inhibitors #Pharmacolgy #Pathophysiology #MechanismOfAction
Inhibitors of Platelet ... #Pharmacolgy #Pathophysiology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Usually normal platelet
Causes of Thrombocytopenia. Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... due to increased platelet ... #Differential #Causes
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 Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... patients if the cause ... Thrombocytopenia #Platelet ... Differential #Diagnosis #Causes
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