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diagnosis differential hematology treatment workup thrombocytopenia criticalcare gastroenterology nephrology neurology checklist hepatology anticoagulation cardiology obstetrics peds pregnancy pulmonary table obgyn
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... Intracranial hemorrhage Management ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... Prophylactically for platelet ... not transfuse platelets ... Platelet transfusions ... #RBCs #Platelets
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Differential #Diagnosis #causes ... #Platelets #hematology
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
Thromboelastography (TEG) Based Management ... cryoprecipitate - If platelets ... < 50 -> platelet ... Thromboelastography #TEG #Management
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
based therapy and Management ... cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastography #TEG #Management
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... vs Acquired #Bleeding ... Differential #Diagnosis #Algorithm
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Transfusion of Platelets ... procedure, no active bleeding ... Surgery with active bleeding ... procedure - < 20 #Management ... #Platelets #Transfusion
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 Causes of Acquired Platelet Dysfunction #Acquired #Platelet #Dysfunction #Causes #differential #Diagnosis #hematology
Causes of Acquired ... Platelet Dysfunction ... #Acquired #Platelet ... #Dysfunction #Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... - History of bleeding ... epistaxis, gingival bleeding ... Thrombocytopenia #Platelet
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