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Pulmonary complications of targeted therapy -Immune checkpoint inhibitors (e.g. pembrolizumab) -Pneumonitis is uncommon (~5% of patients) but can
pembrolizumab) -Pneumonitis ... associated with a clinical ... diagnosis pneumonitis ... #Clinical #Diagnosis ... #Radiology #Honc
Nodular pattern 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary TB: random nodules 3. Sarcoidosis: nodules with perilymphatic
Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... #Clinical #Radiology
Chronic hypersensitivity pneumonitis The key findings in chronic hypersensitivity pneumonitis are: Mosaic pattern with areas of ground-glass atenuation
hypersensitivity pneumonitis ... hypersensitivity pneumonitis ... hypersensitivity pneumonitis ... #Clinical #Radiology ... Hypersensitivity #Pneumonitis
Exposure Related ILD • Hypersensitivity pneumonitis • Pneumoconioses • Radiation pneumonitis • Medication-induced ILD Andrew Sanchez
Hypersensitivity pneumonitis ... • Radiation pneumonitis
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Hypersensitivity pneumonitis ... • Radiation pneumonitis ... Idiopathic Interstitial Pneumonias
Cystic Lung Disease Upper Lobe Predominant: Langerhans Cell Histiocytosis, Pneumocystis Jiroveci, Hypersensitivity Pneumonitis, Neurofibromatosis Type 1, Paracoccidioidomycosis,
Hypersensitivity Pneumonitis ... Lymphocytic Interstitial Pneumonitis ... Desquamative Interstitial Pneumonitis
On the left some diseases with a nodular pattern. 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary
Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... #Clinical #Diagnosis ... #Radiology #Pulmonary
More common & convincing pneumonia mimics Aspiration pneumonitis, Pulmonary vasculitis, Acute eosinophilic pneummia, Cryptogeric organizing
Aspiration pneumonitis ... Drug -induced pneumonitis
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
Non-Resolving Pneumonias ... Hypersensitivity pneumonitis
Upper lung zone preference is seen in: - Inhaled particles: pneumoconiosis (silica or coal) - Smoking related diseases
Hypersensitivity pneumonitis ... edema #Diagnosis #Radiology
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