21 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... half-life = 40 days ([HCQI ... (e.g. renal failure ... #rheumatology #pharmacology ... levels #lupus #management
Hydroxychloroquine and Chloroquine in COVID19

Dosing:
Hydroxychloroquine:
 - 400mg PO BID on the first day, followed by 200mg
Hydroxychloroquine ... COVID19 Dosing: Hydroxychloroquine ... Chloroquine #COVID19 #HCQ ... #Pharmacology # ... Management #Medications
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... Chloroquine - Hydroxychloroquine ... QRS #widening #ECG ... #EKG #Pharmacology ... Differential #Drugs #Classes
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
side effects (e.g ... tinnitus) and may cause ... It also can cause ... prolonging drugs (e.g ... #HCQ #Pharmacology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
ophthalmology MD input) - Hydroxychloroquine ... HCQ treatment would ... Treatment #COVID19 #Pharmacology ... #Table #Management
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... rare with ~100 cases ... Lupusreference #Hydroxychloroquine ... #hcq #Risks #Benefits ... #Lupus #pharmacology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... patients with HCM ... patients with HCM ... Bradyarrhythmias, Some cases ... comparison #table #pharmacology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... • Higher doses cause ... cAMP/cGMP • Causes ... Vasopressors #Inotropes #Pharmacology ... #Summary #management
OPIOID SWITCHING AND TAPERING.

Long term opioid use results in physical (and potentially psychological) dependence. Opioids should
symptoms include: chills ... sweating, anxiety, nausea ... tapering #switching #pharmacology ... #conversion #management
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Resistance, Main Uses ... 0.375-0.75 mcg/kg ... high 10-20 mcg/kg ... Properties #Table #Pharmacology ... #Effect #Management