27 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... • Higher doses cause ... cAMP/cGMP • Causes ... #Summary #management
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... agent • Does not cause ... side effects (e.g ... #Summary #DM2 #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Summary Mechanisms ... side effects (e.g ... not definitively cause ... #Summary #DM2 #
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
stagnant hypoxia (e.g ... carrying capacity (e.g ... Hypoxia #Hypoxemia #summary ... differential #diagnosis #causes ... #pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Pathophysiology: ... PhysicalExam #clinical #neurology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Diagnosis #Algorithm #causes
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
, asthenia • Neurologic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
for reversible cause ... Lorazepam 0.1 mg/kg ... Phenytoin 20 mg/kg ... Algorithm #Management #Neurology ... #Pharmacology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
alpha-1 blockers (e.g ... -5 inhibitors (e.g ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology