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hematology syndrome blood chronic cirrhosis failure gastroenterology hepatorenal hrs hrsaki hrsckd hrsnaki induced leukostasis liver lung lysis product pulmonary reactions
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Kidney Failure Coagulation ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... #diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... (Acute: previously ... structural kidney injury ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
cytotoxic lung injury ... pleural effusions • Acute ... acute respiratory ... Exclude other causes ... #management #Toxicology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... unless worrisome EKG ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... - Acute Hemolytic ... Lung Injury (TRALI ... #Transfusions #diagnosis ... #management #hematology
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