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diagnosis differential nephrology aki management chronic classification hepatitis acidosis aclf acutekidneyinjury blood chemistry cirrhosis criticalcare dili druginduced elevation emergency fatigue
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure ( ... Kidney Failure ... Infections Alcohol-Associated ... Injury (DILI) ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... HSV • Toxic: Alcohol ... #Acute #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... #Algorithm #hepatology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... failure (a.k.a. ... tubular necrosis (causes ... #Kidney #Injury
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes ... of Acute Liver ... ALT Ratios: • Alcoholic ... #hepatology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Common causes of ... Acute Kidney Injury ... HEMODYNAMIC • Cardiac failure ... Tubular Injury/ ... NephroP #AKI #causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure ( ... ALT Ratios: • Alcoholic ... cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... #differential #Hepatology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Moyamoya • Toxic: Alcohol ... Traumatic brain injury ... Hypoxia, Uremia, Liver ... failure, Eclampsia ... #Causes #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... • Liver Failure ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... Alcohol) • Drug
Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
Causes of Polyuria ... concentration (e.g ... Recovery from Acute ... Renal Failure, ... #Causes
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