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diagnosis peds algorithm blood product reactions syndrome treatment abscess alcoholic anemia aplastic bleeding capillary child children clarksons crisis differential disease
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... Non-accidental Injury ... neurology, back pain Haematology ... cell disease Rheumatology ... #Child #Peds #Pediatrics
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Common bacterial causes ... Hepatic artery (e.g ... ) • Traumatic injury ... liver #abscess #pediatrics ... differential #diagnosis #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... Related Acute Lung Injury ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
) Acute kidney injury ... endothelial cell injury ... of arteries Management ... • Refractory cases ... Renal #Crisis #rheumatology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... non-accidental injury ... connective tissue, e.g ... History #peds #pediatrics ... #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... • Thrombosis (e.g ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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