13 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Chronic inflammatory disorders ... (e.g. autoimmune ... #hematology #secondary
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... changes), high MCV anemia ... primary hematologic disorder ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Increased Requirement (e.g ... • Small Bowel Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... lymphoproliferative disorders ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Marrow (Toxic injury ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... the most common cause ... , eg, cyclic neutropenia ... Megaloblastic anemia-rare ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Drug history, e.g ... non-accidental injury ... connective tissue, e.g ... History #peds #pediatrics ... #diagnosis #hematology