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diagnosis differential fusarium treatment bloodculture endocarditis infective negative prs pulmonary renal syndromes
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
microbiological techniques Work-up ... but important causes ... special stains (e.g ... #differential #workup ... #infectiousdiseases
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
BCx+ in -40% of cases ... ; triazole (e.g. ... on the type of injury ... #infectiousdiseases ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... quantify renal injury ... confirm DAH, r/o infection ... Goodpasture's cause ... differential #diagnosis #management
Fusarium Treatment • Antifungal "susceptibility" can vary with Fusarium spp • F. oxysporum: low MICS to
amphotericin B for severe cases ... ; triazole (e.g. ... on the type of injury ... #infectiousdiseases ... #management #treatment
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