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Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis (Scleroderma ... 3 Subtypes of Scleroderma ... Sclerosis sine scleroderma ... telangiectasias, poikiloderma ... HTN) • Renal: scleroderma
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Systemic sclerosis or scleroderma ... systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... Systemic sclerosis/scleroderma ... rheumatology #diagnosis #differential
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis (Scleroderma ... 10% - 15% • Scleroderma ... Systemic #Sclerosis #Scleroderma
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Scleroderma Like ... Conditions - Differential ... reduced incidence Scleredema ... - Can produce scleroderma-like ... #Differential #
ILD of Known Cause - Differential Diagnosis Exposure: • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis • Treatment Related:
Known Cause - Differential ... Tissue Disease: RA, Scleroderma ... #ILD #Causes #Differential
Scleroderma Mimics • Scleredema • Scleromyxedema (papular mucinosis) • Eosinophilic Fasciitis • Nephrogenic Systemic Fibrosis •
Scleroderma Mimics ... • Scleredema ... @MithuRheum #Scleroderma ... #rheumatology #differential
Chronic Diarrhea Differential Diagnosis • Inflammatory, Infectious: Recurrent C. diff, Giardiasis • Inflammatory, Non-infectious: IBD, Ischemia,
Chronic Diarrhea Differential ... Thyrotoxicosis, Scleroderma ... Diarrhea #Chronic #Differential
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hypertension • Scleroderma ... #schistocytes #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... Systemic sclerosis/scleroderma ... Systemic Sclerosis (scleroderma ... rheumatology #diagnosis #differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... #skin #rashes #differential
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