16 results
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
disorders of Liver & Lung ... Malignancies • Aging ... #Factor #RF #rheumatology ... #laboratory #differential ... #diagnosis
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
pain / swelling ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #Arthritis #diagnosis ... #management #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Pain Rash ... rheumaticum • Rheumatic ... #pain #skin #rashes ... #differential # ... diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Shrinking lung ... System Tender points ... #pain #differential ... #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Generally affects long ... • Differentiate ... #Disease #differential ... #diagnosis #causes ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Pain History ... in persons with rheumatoid ... #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... - Autoimmune Rheumatologic ... #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... bacterial), acute rheumatic ... • Key point: If ... #Joint #Pain #MSK ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
skin lesions + Rheumatic ... pain Clinical ... thickening • Osteitis: pain ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... pain • Swan neck ... #Rheumatology