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differential arthritis joint msk rheumatoid testing aids approach autoimmune bronchiectasis emergencies extraarticular hemeonc infections infectiousdiseases laboratory monoarthritis monoarticular myopathy myositis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... cause interstitial lung ... disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... of Joint Disease ... rheumatoid arthritis (RA ... #Pain #MSK #rheumatology ... #approach #workup
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Rheumatoid #Arthritis #RA ... #Signs #Symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... Parvovirus B19 • HIV ... Symmetrical: • RA
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... weight • Chest pain ... Nasal polyps and signs ... high-resolution chest CT ... , CCP, ANCA • HIV
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Diagnosis Framework ... Disease by CD4 ... • CT: Halo sign ... Constitutional symptoms ... #AIDS #pulmonary
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Additional tests: HIV ... titer, ACE level, CXR ... , and low back pain ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... involvement, abdominal pain ... #Rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... chest; CT abdomen ... if abdominal pain ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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