12 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis ... Differential Diagnosis ... weeks) Can Be Caused ... Joint #pain #Differential ... #Diagnosis #MSK
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... - Differential Diagnosis ... with Activity ( ... e.g. fractured long ... #Orthopedics #Causes
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... titer, ACE level, CXR ... , and low back pain ... (to support a diagnosis ... #testing #Rheumatology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
pressure to the point ... compartment Fat Embolism ... Syndrome • Syndrome caused ... • Diagnosis: ... function and reflex activity
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Joint pain ... Erythematosus #Diagnosis ... #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
increased B-cell activity ... granulomas within the lungs ... symptoms are not caused ... e.g. incidental CXR ... Extrapulmonary: ankle arthritis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... , fever, joint pain ... manifestations, hypoxia, CXR ... #Oncology #Diagnosis
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... proximal muscle pain ... with restricted active ... for giant cell arteritis ... #Management #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... pain, chest pain ... Urinary antigen testing ... change in the lungs ... Meningitis, septic arthritis