17 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Idiosyncratic - less common ... ongoing ↑ LFTs or symptoms ... #algorithm #gastroenterology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
and Management ... Insufficiency: Most Common ... ketoconazole, etomidate) Symptoms ... Insufficiency: Long-term ... hypophysitis, Sheehan's syndrome
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... • Dyspnea - Common ... resolution of symptoms ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... gradually with symptoms ... - Pulmonary embolism ... Improvement in symptoms ... #management #Toxicology
ECMO Troubleshooting - OnePager Summary
ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
• HYPOXEMIA is common ... or membrane lung ... POST-CANNULATION SYNDROME ... Troubleshooting #problems #diagnosis ... #differential #management
Mild-to-Moderate Ulcerative Colitis - Management Algorithm
Curcumin:
 • Natural phytochemical from turmeric
 • 2g/day divided in 2-3
Ulcerative Colitis - Management ... Potential GI SE, liver ... Nissle • VSL#3: ↑ clinical ... delivery to the colon ... Budesonide to induce
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... disease • Liver ... : • Nephrotic syndrome ... #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... granulomas within the lungs ... renal failure Clinical ... heart (2-5%), liver ... #Management #Signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... rash) • Heart, lung ... Sepsis • Drug-induced ... thrombocytopenia • Liver ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... HLH signs and symptoms ... can mimic common ... lymph node, or liver