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diagnosis hematology management leukemia chronic mds myelodysplastic arteritis classification common cvid differential gca giantcell hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology infections
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... • Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... -> AML: Blast crises ... - infiltrates (anemia ... lymphoid organs When Cancer ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... immunophenotype Clinical ... 5) Symptoms of anemia ... uw_IMresidency #CLL ... #Leukemia #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... anemia Treatment ... #Anemia #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... factor (GCSF) treatments ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA ... Start steroids if concern
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... disease, alcohol, cancer ... Bone Marrow - Anemia ... Pulmonary Disease: Clinical ... Lung Disease: • Clinical
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