8 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... dechallenge • Acute ... hepatitis #DILI #DrugInduced ... #Liver #Injury ... Diagnosis #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... range: 18 wks - postpartum ... = nonspecific (nausea ... headache, malaise) → Acute ... #Pregnancy #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
deficiency • Liver ... deficiencies - PNH ... - APLS • Acute ... fever • Drug reactions ... Differential #Diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... Lupusreference #druginduced ... #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... Transfusions #diagnosis #management ... #hematology #reactions
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
terbinafine, thiazidic, PPI ... • Immunologic Workup ... Discontinuation of causal ... Lupusreference #DrugInduced ... diagnosis #treatment #management
Artificial Liver Support Systems
Bridge between transplantation to allow a patient's liver to recover
When used: Acute liver
recover When used: Acute ... Acute-on-chronic ... Similar to MARS but uses ... Hemodiafiltration - Works ... #management