9 results
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Clopidogrel to Prasugrel ... De-escalation in Potency: Prasugrel ... High Potency: Prasugrel ... Ticagrelor to Prasugrel ... antiplatelet #ticagrelor #prasugrel
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors
A, Switching between oral agents in the acute/early phase.
escalating to prasugrel ... hours after last prasugrel ... ticagrelor to prasugrel ... antiplatelet #ticagrelor #prasugrel
Trends in Platelet Adenosine Diphosphate P2Y12 Receptor Inhibitor Use and Adherence Among Antiplatelet-Naive Patients After Percutaneous
#Clopidogrel #Prasugrel
Antiplatelet Conversion - P2Y12 Inhibitor Switching
 • Clopidogrel (Plavix)
 • Prasugrel (Effient)
 • Ticagrelor (Brilinta)
Clopidogrel and
Clopidogrel (Plavix) • Prasugrel ... Clopidogrel and prasugrel ... clopidogrel and prasugrel ... clopidogrel and prasugrel
Oral P2Y12 Inhibitor Pharmacology

 • Clopidogrel
 • Prasugrel
 • Ticagrelor

By Kyle Fischer, PharmD @Kfischer_10

#P2Y12 #Inhibitor #Pharmacology
Clopidogrel • Prasugrel
Very Quick Guide to Reversing Antithrombotic Therapy
Aspirin 
Clopidogrel 
Prasugrel 
Ticagrelor 
Abciximab 
Tirofiban 
Eptifibatide 
Unfractionated Heparin 
Low
Clopidogrel Prasugrel
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy
Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
, Clopidogrel, Prasugrel
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
(clopidogrel, prasugrel
Cangrelor - Pharmacology
Cangrelor (Kengreal) is a parenteral analogue of adenosine triphosphate
Cangrelor binds reversibly to the platelet
Antiplatelet: • Both prasugrel ... clopidogrel and prasugrel