9 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... interferes with the activity ... mitochondrial electron ... kidney injury are ... Toxicology #Diagnosis #Management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Pearls: • IDA and active ... NRH & Heme eval. re ... ileal Crohn's/resection ... have fatigue w/ active ... #diagnosis #management
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... recommended for routine screening ... and specific for detection ... disorders that activate ... #glomerular #testing
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... signs/symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology ... excisional biopsy - Detection
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... malignancy Pathophysiology ... • Pituitary testing ... Transsphenoidal surgical resection ... Endocrinology #Treatment #Pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... disorders that activate ... recommended for routine screening ... and specific for detection ... diagnosis #initial #testing
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
incidentaloma/periodic screening ... resistance, impaired fasting ... - First, a non-selective ... laparoscopic tumor resection ... Open surgical resection
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
Colorectal Cancer Screening ... Colonoscopy: 100% detection ... #Tests #comparison ... #table #management ... gastroenterology #CRC #Testing
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
Colorectal Cancer Screening ... Colonoscopy: 100% detection ... Indications #Tests #comparison ... #table #management ... gastroenterology #CRC #Testing