22 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... Langerhans giant cells are ... Active TB: •
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... terminal alveoli and are ... inhibitors • Injection ... Langerhans giant cells are ... Active TB: •
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... IGRA/QuantiFERON-TB ... single specimen are ... Testing #Diagnosis #Workup ... #TB #Latent #Active
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Typically from TB ... signs/symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology ... excisional biopsy - Detection
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
individual with active ... TB • Abnormal ... consistent with old TB ... kidney disease and are ... Underweight • Injection
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
thrombophilias are ... surgery, trauma, active ... - No other workup ... Hypercoagulable #Workup ... hematology #diagnosis #algorithm
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... interferes with the activity ... mitochondrial electron ... kidney injury are
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Fatigue and IBD Algorithm ... Pearls: • IDA and active ... NRH & Heme eval. re ... ileal Crohn's/resection ... have fatigue w/ active
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... node and AV node activity ... ACCP Cardiology PRN ... #Pharmacology #Classification ... #Classes #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Antigen-antibody complexes are ... tissues where they activate ... Antigen-presenting cells activate ... Tuberculin test, Graft rejection ... allergy #table #classification