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management differential approach comparison druginduced joint pain pathophysiology sle syndrome treatment workup activation causes classification degenerative dil erythematosus gait gout
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
e.g., meniscal tears ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis ... #arthritis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... #Rheumatology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
of the Hip • Arthritis ... Trauma • Strains/ tears ... Valgus position of knee ... symptoms #signs #diagnosis ... #msk
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Heart, lung, and kidney ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... Polyarteritis Nodosa: - Kidneys ... such as systemic lupus ... Kidneys -> glomerulonephritis ... #rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
in Rheumatoid arthritis ... , Lupus, etc) -> ... commonly affects the knee ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... #DIL #rheumatology ... #diagnosis #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Symptomatic: artificial tears ... Sjogrens #Syndrome #Rheumatology
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