14 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology of Diabetic ... Ketoacidosis (DKA ... Hyperosmolar Syndrome (HHS ... #comparison #endocrinology ... #diabetes #diabetic
Diabetic Ketoacidosis 
Management Priorities
1. Fluids 
2. Insulin 
3. Potassium 
4. Acidosis 
5. Re-establish oral fluids,
Diabetic Ketoacidosis ... Identification and treatment ... an underlying cause ... #DKA #Diabetic ... #Ketoacidosis #Diabetes
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
patients with type 2 diabetes ... have new-onset diabetes ... previously established diabetes ... are Euglycemic Diabetic ... #DKA #EDKA #Insulin
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Diabetic ketoacidosis ... (DKA) - caused ... • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... • Gestational Diabetes ... macrosomic infant • Secondary ... Causes: Endocrinopathies ... @AmyChung #Diabetes
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Algorithm for DKA ... /HHS Diagnostic ... Crisis #Algorithm #management ... #endocrinology ... #Diabetes #DM2 #
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... along with IV insulin ... ensure patient has ... pathophysiology #endocrinology ... #diabetes
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... mechanism helps lower primarily ... #Pharmacology #Management ... #Diabetes #DM2 ... #Endocrinology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Increased plasma insulin ... (treatment of diabetic ... thiazide-like diuretics), Primary ... hyperaldosteronism, Secondary
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... conditions, serum BHB has ... drips unless also diabetic ... DKA is essentially ... differential #algorithm #management