17 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Pre-formed lgE binds ... allergen, creating ... an allergen-antibody ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... binds to the lgE ... or IgM antibody binds ... Classification #Pathophysiology ... #Allergy #Diagnosis
Plantar Reflex (Babinski) Equivalents
Plantar toe reflex - Babinski - Move an object along the lateral aspect
Plantar Reflex (Babinski ... Plantar toe reflex - Babinski ... Pinprick-toe reflex - Bing ... and release #Diagnosis ... #PhysicalExam #Babinski
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... Exposure -> Antigen binds ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Antigen binds receptor ... (i.e. heparin) binds ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
myoclonic seizure, primitive ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... /mL, metformin binds ... anaerobic metabolism Diagnosis ... Toxicity #Toxicology #Diagnosis
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
IF-Cbl complex binds ... Differential #Causes #Diagnosis ... #Pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... ♀, ↑Age, ESRD Pathophysiology ... : • IgG binds ... thrombocytopenia Diagnosis ... Thrombocytopenia #Diagnosis