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diagnosis differential leukemia management chronic classification cll hodgkins workup algorithm dermatology disorders hemeonc lymphomas lymphoproliferative mds myelodysplasia myelodysplastic nonhodgkin nonhodgkins
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Distribution - better prognosis ... Rich, Lymphocyte ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphoma (Richter ... transformation) Treatment ... AIHA, PRCA) • Treatment ... #Leukemia #oncology ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoma (SLL) ... Lymphoma (SLL) ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Comparison ... • Prognosis: ... • Other hematologic ... #NonHodgkins #comparison ... #oncology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... Treatment • Early ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... UIP, NSIP): • Lymphocytic ... Nephrogenic DI Hematologic ... • B cell lymphoma ... Adenocarcinoma Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
correlates with prognosis ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
biopsy demonstrates lymphocytes ... , plasma cells, ... the mainstay of treatment ... Differential #Diagnosis #comparison ... #table #dermatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Bone marrow Treatment ... as required Prognosis ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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