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diagnosis anemia algorithm causes classification cold disease extravascular hemolysis hodgkins intravascular management oncology pancytopenia platelets thrombocytosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... younger pts) Differential ... #disease #hemolytic ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
e.g. lupus, CLL, lymphoma ... . primary cold agglutin ... disease, Copper and ... Extravascular #Causes #differential ... #diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
telomeropathy Cancer ... • Leukemia • Lymphoma ... Inflammatory and ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Malignancy: Metastatic cancer ... , Lymphoma, Rebound ... Diagnosis #Algorithm #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... from germinal center ... normal germinal center ... Immunohistochemical studies (to differentiate ... classification #hematology
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