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diagnosis differential algorithm alkalosis hypokalemia metabolic pathophysiology urinary low management metabolicalkalosis nongap potassium urine
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... gene that encodes thiazide-sensitive ... sodium-chloride ... #nephrology #diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... major sweating • Thiazide ... furosemide-like lesion) • Gitelman ... Differential #Diagnosis #Causes ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... Absent: Loop and thiazide ... , Gitelman syndrom ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... use of loop or thiazide ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... Diagnosis #Algorithm #causes
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... sodium chloride ... sodium chloride ... patients with thiazide ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
use of loop or thiazide ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... the indicated causes ... urine #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
Causes of Metabolic ... Diuretics (loop/thiazide ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... diuretic use), Gitelman's ... thiazide diuretic ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
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