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diagnosis signs differential causes rheumatology addisons cushings diabetes diabeticketoacidosis disease dka evaluation hormone hypercortisolism hypertension hyperthyroidism hypokalemia incidentaloma indications insufficiency
Adrenal Incidentalomas: Hormone Evaluation • Zona Glomerulosa: Primary Hyperaldosteronism? - Aldosterone and renin
Adrenal Incidentalomas ... Zona Glomerulosa: Primary ... Aldosterone and renin if hypokalemia ... Evaluation #Diagnosis #workup ... #endocrinology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... vomiting • Fatigue Signs ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... hypertension and signs ... bruit or signs ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... Hepatic: PBC (primary ... #symptoms #testing ... #workup
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... ↑ T3 - Mild hypercalcemia ... #differential #endocrinology ... #signs #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
not a feature of primary ... Cataracts Labs: Hypokalemia ... Imaging: 1) Primary ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
To prevent hypokalemia ... patient has good renal ... Signs/Symptoms/Complications ... pathophysiology #endocrinology
Symptoms and Signs of Hypokalemia Cardiovascular - Hypertension - Orthostatic hypotension - Potentiation of digitalis toxicity -
Symptoms and Signs ... of Hypokalemia ... distension - Ileus Renal ... production - Urinary ... #Symptoms #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... tenderness - decreased pulsation ... with GCA or as primary ... Rash, arthritis Primary
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